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doi: 10.3389/fnut.2026.1833045 Received 17 March 2026 Revised 04 April 2026 Accepted 09 April 2026 Published 27 April 2026 Volume 13 - 2026 Edited by Michele Barone, University of Bari Aldo Moro, Italy Reviewed by Alejandro Bruna, Universidad de Playa Ancha, Chile Umesh Singh, Shyam Shah Medical College, India Updates Copyright 2026 Israel, Moed, Abo Fanne, Kedem, Odeh, Rashed, Marzook, Abumouch and Fanne

Metformin HCl extended-release tablets and metformin HCl immediate-release tablets have a similar extent of absorption (as measured by AUC), while peak plasma levels of metformin extended-release tablets are approximately 20% lower than those of metformin immediate-release tablets at the same dose

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Insulin helps your body use sugar from your bloodstream for energy, which keeps blood sugar levels stable