Higher weekly doses were associated with greater average percentage body weight loss, providing a strong rationale for the slow titration to the highest tolerated maintenance dose
GLP3-R is a triple agonist targeting the glucagon-like peptide-1 (GLP-1), glucosedependent insulinotropic polypeptide (GIP), and glucagon receptors
Tirzepatide is a dual-agonist (GLP-1 + GIP)
as an adjunct to diet and exercise regimen to improve glycemic control in patients with type 2 diabetes mellitus who did not achieve adequate control against the background of monotherapy with metformin or sitagliptin, or after unsuccessful combined treatment with two drugs
The real answer is, "it depends." It depends on your technique, your storage, your diluent, and even the initial purity of the peptide itself
Possible mild hormonal increases: Cortisol and prolactin at higher doses [6]