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Interestingly, animal model studies employing dietary choline or TMAO, germ-free mice and microbial transplantation confirmed a role for gut microbiota-dependent TMAO production in modulating platelet hyperresponsiveness and thrombotic potential (78)

Metabol-Clin Exp (1999) 48:3859

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Altogether, this contributes to neuroinflammation, oxidative damage, and neuronal death, all of which are observed in PD (La Vitola et al., 2024

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