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Risk factors for cataract vary worldwide, of which, emerging evidence suggests that cumulative deposition of ROS and disruption of redox homeostasis in lens play a very critical role in the pathogenesis and treatment of age-related cataractogenesis (75, 86, 87)

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Within the complex, p53 TAD2 residues 47 to 54 displayed increased rigidity upon binding and consistently maintain an -helical conformation throughout the MD calculations (Fig

Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration

The cells were maintained in a humidified incubator at 37 C and 5% CO 2

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