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It works by directly inhibiting the activation of aggressive inflammatory pathways (like NF-kappaB and MAP kinase) and decreasing the secretion of pro-inflammatory cytokines

Oliveira TT, Coutinho LG, de Oliveira LOA et al (2022) APE1/Ref-1 role in inflammation and immune response

BPC-157 appears to counteract oxidative stress damage through enhancement of antioxidant enzyme systems and reduction of reactive oxygen species in damaged tissues