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Advise patients to monitor glucose daily when initiating TOUJEO [see Warnings and Precautions (5.2)]

These two domains are adjacent to each other on the enzyme, and together form the active site of the GST where the redox reaction occurs

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Importantly, the gastric-slowing effect often diminishes with continued use (tachyphylaxis)

Once your B12 levels have stabilised, continuing injections every few weeks or months can help maintain their positive effects, ensuring energy levels and overall health remain consistent

10.1210/jcem.79.2.7519191 51 HollowayL.KohlmeierL.KentK.MarcusR